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Venlafaxine Hydrochloride

Also sold as Venlafaxine Hydrochloride, Venlafaxine hydrochloride

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. Closely monitor all antidepressant-treated patients for clinical worsening, and emergence of suicidal thoughts and behaviors [see Warnings and Precautions (5.
8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Venlafaxine hydrochloride extended-release capsules are indicated in adults for the treatment of: Major Depressive Disorder (MDD) [see Clinical Studies (14. 1) ] Generalized Anxiety Disorder (GAD) [see Clinical Studies (14.

How to take it

Indication Starting Dose Target Dose Maximum Dose MDD ( 2. 2 ) 37.

Important warnings

Serotonin Syndrome : Increased risk when co-administered with other serotonergic agents, but also when taken alone. If it occurs, discontinue venlafaxine hydrochloride extended-release capsules and serotonergic agents and initiate supportive treatment ( 4 , 5.

Common side effects

The following adverse reactions are discussed in more detail in other sections of the labeling: Hypersensitivity [see Contraindications (4) ] Suicidal Thoughts and Behaviors in Adolescents and Young Adults [see Warnings and Precautions (5. 1) ] Serotonin Syndrome [see Warnings and Precautions (5.

Interactions

7.

If pregnant or breastfeeding

8.

Forms & strengths

100 MG Oral Tablet · 25 MG Oral Tablet · 37.5 MG Oral Tablet · 75 MG Oral Tablet · 50 MG Oral Tablet

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?