Simvastatin

What it’s used for

Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Drug therapy is indicated as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate.

How to take it

Dose range is 5 to 40 mg/day. ( 2.

Important warnings

Patients should be advised of the increased risk of myopathy including rhabdomyolysis with the 80-mg dose. ( 5.

Common side effects

Most common adverse reactions (incidence ≥5. 0%) are: upper respiratory infection, headache, abdominal pain, constipation, and nausea.

Interactions

Drug Interactions Associated with Increased Risk of Myopathy/Rhabdomyolysis ( 2.

If pregnant or breastfeeding

8.

Forms & strengths

4 MG/ML Oral Suspension · 8 MG/ML Oral Suspension · 40 MG Oral Tablet · 80 MG Oral Tablet · 20 MG Oral Tablet · 5 MG Oral Tablet · 10 MG Oral Tablet · 10 MG Disintegrating Oral Tablet · 20 MG Disintegrating Oral Tablet · 40 MG Disintegrating Oral Tablet · 80 MG Disintegrating Oral Tablet

Questions to ask your doctor or pharmacist

• Is this the right medicine for my condition, and how long should I take it?
• What side effects should I watch for, and which need urgent attention?
• Does this interact with my other medicines, supplements, or alcohol?
• What should I do if I miss a dose or take too much?