Sertraline Hydrochloride

Also sold as Sertraline Hydrochloride, SERTRALINE HYDROCHLORIDE

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Sertraline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need.

2 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Sertraline hydrochloride oral solution is indicated for the treatment of the following [See Clinical Studies (14) ] : Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Posttraumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD) Sertraline hydrochloride oral solution is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of ( 1 ): Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Posttraumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD)

How to take it

2 DOSAGE AND ADMINISTRATION Indication Starting Dosage Maximum Dosage MDD (2. 1) 50 mg per day 200 mg per day OCD (2.

Important warnings

Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. If it occurs, discontinue sertraline hydrochloride and serotonergic agents and initiate supportive treatment.

Common side effects

The following adverse reactions are described in more detail in other sections of the prescribing information: Hypersensitivity reactions to sertraline [See Contraindications (4) ] Disulfiram-alcohol reaction when sertraline hydrochloride oral solution is taken with disulfiram [See Contraindications (4) ] QTc prolongation and ventricular arrhythmias when taken with pimozide [See Contraindications (4) , Clinical Pharmacology (12. 2)] Suicidal thoughts and behaviors [See Warnings and Precautions (5.

Interactions

Protein-bound drugs: Monitor for adverse reactions and reduce dosage of sertraline hydrochloride or other protein-bound drugs (e.

If pregnant or breastfeeding

Forms & strengths

200 MG Oral Capsule · 100 MG Oral Tablet · 25 MG Oral Tablet · 50 MG Oral Tablet · 150 MG Oral Capsule · 20 MG/ML Oral Solution

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?