Propranolol Hydrochloride

What it’s used for

Hypertension Propranolol Hydrochloride Extended-Release Capsules, USP, are indicated in the management of hypertension. They may be used alone or used in combination with other antihypertensive agents, particularly a thiazide diuretic.

How to take it

General Propranolol Hydrochloride Extended-Release Capsules, USP, provide propranolol hydrochloride in a sustained-release capsule for administration once daily. If patients are switched from propranolol hydrochloride tablets to Propranolol Hydrochloride Extended-Release Capsules, USP, care should be taken to assure that the desired therapeutic effect is maintained.

Important warnings

Angina Pectoris There have been reports of exacerbation of angina and, in some cases, myocardial infarction, following abrupt discontinuance of propranolol therapy. Therefore, when discontinuance of propranolol is planned, the dosage should be gradually reduced over at least a few weeks, and the patient should be cautioned against interruption or cessation of therapy without the physician's advice.

Common side effects

The following adverse events were observed and have been reported in patients using propranolol. Cardiovascular Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Interactions

Drug Interactions Caution should be exercised when Propranolol Hydrochloride Extended-Release Capsules, USP, are administered with drugs that have an affect on CYP2D6, 1A2, or 2C19 metabolic pathways.

If pregnant or breastfeeding

Pregnancy Pregnancy Category C In a series of reproductive and developmental toxicology studies, propranolol was given to rats by gavage or in the diet throughout pregnancy and lactation.

Forms & strengths

4.28 MG/ML Oral Solution · 10 MG Oral Tablet · 20 MG Oral Tablet · 40 MG Oral Tablet · 60 MG Oral Tablet · 80 MG Oral Tablet · 10 MG/ML Oral Solution · 1 MG/ML Oral Solution · 16 MG/ML Oral Solution · 160 MG Oral Tablet · 2 MG/ML Oral Solution · 4 MG/ML Oral Solution · 8 MG/ML Oral Solution · 80 MG Oral Capsule · 80 MG/ML Oral Solution · 90 MG Oral Tablet

Questions to ask your doctor or pharmacist

• Is this the right medicine for my condition, and how long should I take it?
• What side effects should I watch for, and which need urgent attention?
• Does this interact with my other medicines, supplements, or alcohol?
• What should I do if I miss a dose or take too much?