Naproxen

Also sold as Naproxen

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events • Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use [ see Warnings and Precautions ( 5.

6 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Naproxen tablets and naproxen sodium tablets are indicated for: the relief of the signs and symptoms of: • rheumatoid arthritis • osteoarthritis • ankylosing spondylitis • Polyarticular Juvenile Idiopathic Arthritis Naproxen tablets and naproxen sodium tablets are also indicated for: the relief of signs and symptoms of: • tendonitis • bursitis • acute gout the management of: • pain • primary dysmenorrhea Naproxen tablets and naproxen sodium tablets are non-steroidal anti-inflammatory drugs indicated for: the relief of the signs and symptoms of: • rheumatoid arthritis • osteoarthritis • ankylosing spondylitis • polyarticular juvenile idiopathic arthritis Naproxen tablets and naproxen sodium tablets are also indicated for: the relief of signs and symptoms of: • tendonitis • bursitis • acute gout the management of: • pain • primary dysmenorrhea

How to take it

Use the lowest effective dosage for shortest duration consistent with individual patient treatment goals. ( 2.

Important warnings

Hepatotoxicity : Inform patients of warning signs and symptoms of hepatotoxicity. Discontinue if abnormal liver tests persist or worsen or if clinical signs and symptoms of liver disease develop.

Common side effects

The following adverse reactions are discussed in greater detail in other sections of the labeling: • Cardiovascular Thrombotic Events [ see Warnings and Precautions ( 5. 1 ) ] • GI Bleeding, Ulceration, and Perforation [ see Warnings and Precautions ( 5.

Interactions

See Table 1 for clinically significant drug interactions with naproxen.

If pregnant or breastfeeding

Forms & strengths

250 MG Delayed Release Oral Tablet · 220 MG Oral Capsule · 200 MG Oral Tablet · 375 MG Oral Tablet · 250 MG Oral Tablet · 500 MG Oral Tablet · 500 MG Rectal Suppository · 25 MG/ML Oral Suspension · 500 MG Delayed Release Oral Tablet · 375 MG Delayed Release Oral Tablet · 275 MG Oral Tablet · 550 MG Oral Tablet · 500 MG / 85 MG Oral Tablet · 220 MG Oral Tablet

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?