Methylprednisolone Acetate, Lidocaine Hydrochloride, Bupivacaine Hydrochloride, Povidine Iodine, Isopropyl Alcohol

Also sold as Dyural 80-LM

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: RISK OF CARDIAC ARREST WITH USE OF BUPIVACAINE HYDROCHLORIDE INJECTION IN OBSTETRICAL ANESTHESIA There have been reports of cardiac arrest with difficult resuscitation or death during use of Bupivacaine Hydrochloride Injection for epidural anesthesia in obstetrical patients. In most cases, this has followed use of the 0.

8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Bupivacaine Hydrochloride Injection is indicated in adults for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Specific concentrations and presentations of Bupivacaine Hydrochloride Injection are recommended for each type of block indicated to produce local or regional anesthesia or analgesia [see Dosage and Administration (2.

How to take it

Not for intrathecal use. ( 2.

Important warnings

Dose-Related Toxicity : Monitor cardiovascular and respiratory vital signs and patient's state of consciousness after injection of Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection. ( 5.

Common side effects

The following clinically significant adverse reactions have been reported and described in the Warnings and Precautions section of the labeling: Cardiac Arrest in Obstetrical Anesthesia [see Warnings and Precautions (5. 1) ] Dose-Related Toxicity [see Warnings and Precautions (5.

Interactions

Local Anesthetics : The toxic effects of local anesthetics are additive.

If pregnant or breastfeeding

Forms & strengths

0.01 MG Topical Gel · 2000 MG Injection · 20 MG/ML Injectable Suspension · 40 MG/ML Injectable Suspension · 80 MG/ML Injectable Suspension · 125 MG Injection · 500 MG Injection · 1000 MG Injection · 2 MG Oral Tablet · 32 MG Oral Tablet · 8 MG Oral Tablet · 100 MG Oral Tablet · 4 MG Oral Tablet · 40 MG Injection · 62.5 MG/ML Injectable Solution · 16 MG Oral Tablet

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?