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Losartan Potassium And Hydrochlorothiazide

Also sold as Losartan Potassium and Hydrochlorothiazide

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: FETAL TOXICITY When pregnancy is detected, discontinue losartan potassium and hydrochlorothiazide tablets as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus [see Warnings and Precautions ( 5.
8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Losartan potassium and hydrochlorothiazide tablet is a combination of losartan, an angiotensin II receptor blocker (ARB) and hydrochlorothiazide, a diuretic indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

How to take it

Hypertension Usual starting dose: 50/12. 5 mg once daily.

Important warnings

Hypotension: Correct volume or salt depletion prior to administration of losartan and hydrochlorothiazide. ( 5.

Common side effects

Most common adverse reactions (incidence ≥2% and greater than placebo) are dizziness, upper respiratory infection, cough, and back pain. ( 6.

Interactions

Agents increasing serum potassium: Risk of hyperkalemia.

If pregnant or breastfeeding

8.

Forms & strengths

10 MG/ML Oral Suspension · 100 MG Oral Tablet · 25 MG Oral Tablet · 50 MG Oral Tablet

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?