Lorazepam

Also sold as Lorazepam, LORAZEPAM

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS • Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of these drugs for patients for whom alternative treatment options are inadequate.

7 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Lorazepam tablets are indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

How to take it

Lorazepam tablets are administered orally. For optimal results, dose, frequency of administration, and duration of therapy should be individualized according to patient response.

Important warnings

Risks from Concomitant Use with Opioids Concomitant use of benzodiazepines, including lorazepam, and opioids may result in profound sedation, respiratory depression, coma, and death. Because of these risks, reserve concomitant prescribing of these drugs in patients for whom alternative treatment options are inadequate.

Common side effects

Most adverse reactions to benzodiazepines, including CNS effects and respiratory depression, are dose dependent, with more severe effects occurring with high doses. In a sample of about 3500 patients treated for anxiety, the most frequent adverse reaction to lorazepam was sedation (15.

Interactions

Drug Interactions The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration.

If pregnant or breastfeeding

Pregnancy Pregnancy Exposure Registry There is a pregnancy registry that monitors pregnancy outcomes in women exposed to psychiatric medications, including lorazepam, during pregnancy.

Forms & strengths

0.5 MG Oral Tablet · 1 MG Oral Tablet · 2 MG Oral Tablet · 2.5 MG Oral Tablet · 2 MG/ML Injectable Solution · 4 MG/ML Injectable Solution · 2 MG/ML Oral Solution

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?