Levothyroxine Sodium

Also sold as Levothyroxine sodium, levothyroxine sodium, Levothyroxine Sodium, Unithroid, THYQUIDITY

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS Thyroid hormones, including levothyroxine sodium, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction.

8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Hypothyroidism Levothyroxine sodium tablets are indicated in adult and pediatric patients, including neonates, as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism. Pituitary Thyrotropin (Thyroid‑Stimulating Hormone, TSH) Suppression Levothyroxine sodium tablets are indicated in adult and pediatric patients, including neonates, as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.

How to take it

Administer once daily, preferably on an empty stomach, one-half to one hour before breakfast with a full glass of water. (2.

Important warnings

Serious risks related to overtreatment or undertreatment with levothyroxine sodium tablets: Titrate the dose of levothyroxine sodium carefully and monitor response to titration. (5.

Common side effects

Adverse reactions associated with levothyroxine sodium therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see Warnings and Precautions (5) and Overdosage (10) ]. They include the following: General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia Musculoskeletal: tremors, muscle weakness, muscle spasm Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest Respiratory: dyspnea Gastrointestinal: diarrhea, vomiting, abdominal cramps, elevations in liver function tests Dermatologic: hair loss, flushing, rash Endocrine: decreased bone mineral density Reproductive: menstrual irregularities, impaired fertility Seizures have been reported rarely with the institution of levothyroxine therapy.

Interactions

See full prescribing information for drugs that affect thyroid hormone pharmacokinetics and metabolism (e.

If pregnant or breastfeeding

Forms & strengths

0.1 MG Injection · 0.2 MG Injection · 0.175 MG Oral Capsule · 0.2 MG Oral Capsule · 0.025 MG/ML Oral Solution · 0.05 MG/ML Oral Solution · 0.075 MG/ML Oral Solution · 0.088 MG/ML Oral Solution · 0.1 MG/ML Oral Solution · 0.112 MG/ML Oral Solution · 0.125 MG/ML Oral Solution · 0.013 MG/ML Oral Solution · 0.137 MG/ML Oral Solution · 0.15 MG/ML Oral Solution · 0.175 MG/ML Oral Solution · 0.2 MG/ML Oral Solution · 0.02 MG/ML Oral Solution · 0.0625 MG/ML Oral Solution · 0.0375 MG/ML Oral Solution · 0.044 MG/ML Oral Solution · 0.03 MG/ML Oral Solution · 0.0375 MG Oral Capsule · 0.044 MG Oral Capsule · 0.0625 MG Oral Capsule

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?