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Levofloxacin

Also sold as Levofloxacin, levofloxacin

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: BOXED WARNING SECTION WARNING: SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS • Fluoroquinolones, including levofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together [see Warnings and Precautions ( 5. 1 )], including: o Tendinitis and tendon rupture [see Warnings and Precautions ( 5.
8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Levofloxacin is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with infections caused by designated, susceptible bacteria and in pediatric patients where indicated (1, 12. 4).

How to take it

2 DOSAGE & ADMINISTRATION • Administer Levofloxacin Tablets to pediatric patients weighing 30 kg and greater only (2. 1, 2.

Important warnings

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose ( 4 , 5. 7 ) Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses ( 5.

Common side effects

The most common reactions (≥3%) were nausea, headache, diarrhea, insomnia, constipation and dizziness ( 6. 2 ).

Interactions

Interacting Drug Interaction Multivalent cation-containing products including antacids, metal cations or didanosine Absorption of levofloxacin is decreased when the tablets are taken within 2 hours of these products.

If pregnant or breastfeeding

8.

Forms & strengths

250 MG Oral Tablet · 500 MG Oral Tablet · 750 MG Oral Tablet · 5 MG/ML Ophthalmic Solution · 25 MG/ML Oral Solution · 15 MG/ML Ophthalmic Solution

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?