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Ibuprofen And Famotidine

Also sold as IBUPROFEN AND FAMOTIDINE

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use [see Warnings and Precautions (5.
8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Ibuprofen and famotidine tablet, a combination of the NSAID ibuprofen and the histamine H 2 -receptor antagonist famotidine, is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers, which in the clinical trials was defined as a gastric and/or duodenal ulcer, in patients who are taking ibuprofen for those indications. The clinical trials primarily enrolled patients less than 65 years of age without a prior history of gastrointestinal ulcer.

How to take it

Carefully consider the potential benefits and risks of ibuprofen and famotidine tablets and other treatment options before deciding to use ibuprofen and famotidine tablets. Use ibuprofen at the lowest effective dosage for the shortest duration consistent with individual patient treatment goals [see Warnings and Precautions (5)] .

Important warnings

5 WARNINGS AND PRECAUTIONS • Hepatotoxicity : Inform patients of warning signs and symptoms of hepatotoxicity. Discontinue if abnormal liver tests persist or worsen or if clinical signs and symptoms of liver disease develop.

Common side effects

The following serious adverse reactions are discussed in greater detail in other sections of the labeling: Cardiovascular Thrombotic Events [see Warnings and Precautions (5. 1)] GI Bleeding, Ulceration, and Perforation [see Warnings and Precautions (5.

Interactions

See Table 3 for clinically significant drug interactions with ibuprofen.

Forms & strengths

400 MG / 5 MG Oral Tablet · 200 MG / 30 MG Oral Capsule · 200 MG / 30 MG Oral Tablet · 20 MG/ML / 3 MG/ML Oral Suspension · 200 MG / 10 MG Oral Tablet · 0.05 MG Topical Gel · 50 MG/ML Topical Cream · 20 MG/ML Oral Suspension · 300 MG Oral Tablet · 400 MG Oral Tablet · 600 MG Oral Tablet · 800 MG Oral Tablet · 100 MG Oral Tablet · 40 MG/ML Oral Suspension · 200 MG Extended Release Oral Capsule · 400 MG Oral Capsule · 800 MG Extended Release Oral Tablet · 100 MG Chewable Tablet · 200 MG Oral Capsule · 200 MG Oral Tablet · 50 MG Chewable Tablet · 300 MG Extended Release Oral Capsule · 0.1 MG Topical Gel · 0.05 MG / 0.03 MG Topical Gel

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?