Glimepiride
Also sold as Glimepiride
Medicine summary · from official FDA labels · Oct 19, 2026
What it’s used for
Glimepiride Tablet, USP is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies ( 14. 1 )] ].
How to take it
Recommended starting dose is 1 or 2 mg once daily. Increase in 1 or 2 mg increments no more frequently than every 1-2 weeks based on glycemic response.
Important warnings
Hypoglycemia: May be severe. Ensure proper patient selection, dosing, and instructions, particularly in at-risk populations (e.
Common side effects
The following serious adverse reactions are discussed in more detail below and elsewhere in the labeling: Hypoglycemia [see Warnings and Precautions ( 5. 1 ) ] Hemolytic anemia [see Warnings and Precautions ( 5.
Interactions
Certain medications may affect glucose metabolism, requiring glimepiride dose adjustment and close monitoring of blood glucose ( 7.
If pregnant or breastfeeding
8.
Forms & strengths
6 MG Oral Tablet · 8 MG Oral Tablet · 3 MG Oral Tablet · 1 MG Oral Tablet · 2 MG Oral Tablet · 4 MG Oral Tablet · 1 MG / 4 MG Oral Tablet · 2 MG / 4 MG Oral Tablet · 4 MG / 4 MG Oral Tablet · 2 MG / 30 MG Oral Tablet · 4 MG / 30 MG Oral Tablet · 2 MG / 8 MG Oral Tablet · 4 MG / 8 MG Oral Tablet
Questions to ask your doctor or pharmacist
- Is this the right medicine for my condition, and how long should I take it?
- What side effects should I watch for, and which need urgent attention?
- Does this interact with my other medicines, supplements, or alcohol?
- What should I do if I miss a dose or take too much?