Fluoxetine Hydrochloride

Also sold as Fluoxetine

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a reduction in risk with antidepressant use in patients aged 65 and older [see Warnings and Precautions (5.

7 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Fluoxetine is indicated for the treatment of: Acute and maintenance treatment of Major Depressive Disorder [see Clinical Studies (14. 1) ] .

How to take it

Indication Adult Pediatric MDD ( 2. 1 ) 20 mg/day in am (initial dose) 10 to 20 mg/day (initial dose) OCD ( 2.

Important warnings

When using fluoxetine and olanzapine in combination, also refer to the Warnings and Precautions section of the package insert for Symbyax. Suicidal thoughts and Behaviors in Children, Adolescents, and Young Adults: Monitor for clinical worsening and suicidal thinking and behavior ( 5.

Common side effects

The following adverse reactions are discussed in more detail in other sections of the labeling: Suicidal Thoughts and Behaviors in Children, Adolescents, and Young Adults [see Boxed Warning and Warnings and Precautions (5. 1) ] Serotonin Syndrome [see Warnings and Precautions (5.

Interactions

As with all drugs, the potential for interaction by a variety of mechanisms (e.

If pregnant or breastfeeding

Forms & strengths

60 MG Oral Tablet · 60 MG Oral Capsule · 20 MG Oral Tablet · 10 MG Oral Capsule · 20 MG Oral Capsule · 4 MG/ML Oral Solution · 40 MG Oral Capsule · 10 MG Oral Tablet · 90 MG Delayed Release Oral Capsule · 25 MG / 6 MG Oral Capsule · 25 MG / 12 MG Oral Capsule · 50 MG / 12 MG Oral Capsule · 50 MG / 6 MG Oral Capsule · 25 MG / 3 MG Oral Capsule · 8 MG Chewable Tablet · 64 MG Chewable Tablet · 16 MG Chewable Tablet · 32 MG Chewable Tablet

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?