Fenofibrate

What it’s used for

Fenofibrate tablets are peroxisome proliferator receptor alpha (PPARα) activator indicated as an adjunct to diet: • To reduce elevated LDL-C, Total-C, TG and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia ( 1. 1 ).

How to take it

2 DOSAGE & ADMINISTRATION • Primary hypercholesterolemia or mixed dyslipidemia: Initial dose of 145 mg once daily ( 2. 2 ).

Important warnings

5 WARNINGS AND PRECAUTIONS • Myopathy and rhabdomyolysis have been reported in patients taking fenofibrate. The risks for myopathy and rhahdomylosis are increased when fibrates are co-administered with a statin (with a significantly higher rate observed for gemfibrozil), particularly in elderly patients and patients with diabetes, renal failure, or hypothyroidism ( 5.

Common side effects

The most common adverse reactions (> 2% and at least 1% greater than placebo) are abnormal liver tests, increased AST, increased ALT, increased CPK, and rhinitis (6). To report SUSPECTED ADVERSE REACTIONS, contact AvKARE at 1-855-361-3993 or FDA at 1-800-FDA-1088 or www.

Interactions

7 DRUG INTERACTIONS • Coumarin anticoagulants: (7.

If pregnant or breastfeeding

8.

Forms & strengths

100 MG Oral Capsule · 30 MG Oral Capsule · 90 MG Oral Capsule · 67 MG Oral Capsule · 134 MG Oral Capsule · 200 MG Oral Capsule · 160 MG Oral Tablet · 54 MG Oral Tablet · 267 MG Oral Capsule · 145 MG Oral Tablet · 48 MG Oral Tablet · 130 MG Oral Capsule · 43 MG Oral Capsule · 87 MG Oral Capsule · 50 MG Oral Tablet · 150 MG Oral Capsule · 50 MG Oral Capsule · 120 MG Oral Tablet · 40 MG Oral Tablet

Questions to ask your doctor or pharmacist

• Is this the right medicine for my condition, and how long should I take it?
• What side effects should I watch for, and which need urgent attention?
• Does this interact with my other medicines, supplements, or alcohol?
• What should I do if I miss a dose or take too much?