Empagliflozin
Also sold as JARDIANCE, Jardiance
Medicine summary · from official FDA labels · Oct 19, 2026
What it’s used for
1 INDICATIONS AND USAGE JARDIANCE is indicated: to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure. to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease.
How to take it
Assess volume status and correct volume depletion before initiating ( 2. 1 ) Recommended dose is 10 mg once daily in the morning, taken with or without food ( 2.
Important warnings
Ketoacidosis: Assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis, regardless of blood glucose level. If suspected, discontinue JARDIANCE, evaluate and treat promptly.
Common side effects
The following important adverse reactions are described below and elsewhere in the labeling: Ketoacidosis [see Warnings and Precautions (5. 1) ] Volume Depletion [see Warnings and Precautions (5.
Interactions
Table 3 Clinically Relevant Interactions with JARDIANCE Diuretics Clinical Impact Coadministration of empagliflozin with diuretics resulted in increased urine volume and frequency of voids, which might enhance the potential for volume depletion.
If pregnant or breastfeeding
8.
Forms & strengths
5 MG / 500 MG Oral Tablet · 12.5 MG / 500 MG Oral Tablet · 5 MG / 1000 MG Oral Tablet · 12.5 MG / 1000 MG Oral Tablet · 10 MG Oral Tablet · 25 MG Oral Tablet · 10 MG / 5 MG Oral Tablet · 25 MG / 5 MG Oral Tablet
Questions to ask your doctor or pharmacist
- Is this the right medicine for my condition, and how long should I take it?
- What side effects should I watch for, and which need urgent attention?
- Does this interact with my other medicines, supplements, or alcohol?
- What should I do if I miss a dose or take too much?