Empagliflozin And Linagliptin

What it’s used for

1 INDICATIONS AND USAGE GLYXAMBI is a combination of empagliflozin and linagliptin indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus . Empagliflozin is indicated to reduce the risk of cardiovascular (CV) death in adults with type 2 diabetes mellitus and established CV disease [see Clinical Studies (14.

How to take it

Assess renal function before initiating and as clinically indicated. Assess volume status and correct volume depletion before initiating.

Important warnings

Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis: Consider ketone monitoring in patients at risk of ketoacidosis, as indicated. Assess for ketoacidosis regardless of presenting blood glucose levels and discontinue GLYXAMBI if ketoacidosis is suspected.

Common side effects

The following important adverse reactions are described below and elsewhere in the labeling: Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis [see Warnings and Precautions (5. 1) ] Pancreatitis [see Warnings and Precautions (5.

Interactions

Table 3 describes clinically relevant interactions with GLYXAMBI.

If pregnant or breastfeeding

8.

Forms & strengths

5 MG / 500 MG Oral Tablet · 12.5 MG / 500 MG Oral Tablet · 5 MG / 1000 MG Oral Tablet · 12.5 MG / 1000 MG Oral Tablet · 10 MG Oral Tablet · 25 MG Oral Tablet · 10 MG / 5 MG Oral Tablet · 25 MG / 5 MG Oral Tablet

Questions to ask your doctor or pharmacist

• Is this the right medicine for my condition, and how long should I take it?
• What side effects should I watch for, and which need urgent attention?
• Does this interact with my other medicines, supplements, or alcohol?
• What should I do if I miss a dose or take too much?