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Diphenhydramine Hcl

Also sold as Childrens Allergy Relief, Allergy Relief, Nighttime Sleep Aid, basic care nighttime sleep aid

Medicine summary · from official FDA labels · Oct 19, 2026

4 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Use for relief of occasional sleeplessness.

How to take it

Directions adults and children 12 years of age and over: 1 softgel (50 mg) at bedtime if needed, or as directed by a doctor

Important warnings

Warnings Do not use for children under 12 years of age with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product avoid alcoholic drinks.

If pregnant or breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

Forms & strengths

38 MG / 200 MG Oral Tablet · 25 MG / 200 MG Oral Capsule · 50 MG Oral Capsule · 25 MG Oral Tablet · 50 MG/ML Injectable Solution · 0.02 MG Topical Gel · 1.25 MG/ML Oral Solution · 10 MG/ML Topical Cream · 12.5 MG Chewable Tablet · 2.5 MG/ML Oral Solution · 25 MG Oral Capsule · 20 MG/ML Topical Cream · 25 MG / 10 MG Oral Tablet · 50 MG Oral Tablet · 2.5 MG/ML / 1 MG/ML Oral Solution · 20 MG/ML / 1 MG/ML Topical Cream · 25 MG Disintegrating Oral Tablet · 0.02 MG / 0.01 MG Topical Gel · 1.25 MG/ML / 0.5 MG/ML Oral Solution · 20 MG/ML / 10 MG/ML Topical Cream · 1.67 MG/ML Oral Solution · 0.5 MG/ML Injectable Solution · 1 MG/ML Injectable Solution · 2 MG/ML Oral Solution

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?