Diazepam

Also sold as Diazepam, Valtoco

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS • Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of these drugs in patients for whom alternative treatment options are inadequate.

7 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

1 INDICATIONS AND USAGE VALTOCO ® is indicated for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity (i. e.

How to take it

Administer VALTOCO by the nasal route only. ( 2.

Important warnings

Depression: Monitor for central nervous system (CNS) depression. May cause an increased CNS-depressant effect when used with alcohol or other CNS depressants.

Common side effects

The following serious adverse reactions are discussed elsewhere in the labeling: Risk of Concomitant Use with Opioids [see Warnings and Precautions (5. 1) ] Abuse, Misuse, and Addiction [see Warnings and Precautions (5.

Interactions

7 DRUG INTERACTIONS CYP2C19 and CYP3A4 Inhibitors: Elimination of diazepam could be decreased with concurrent administration; therefore, adverse reactions with VALTOCO may be increased.

If pregnant or breastfeeding

Forms & strengths

10 MG Rectal Suppository · 5 MG/ML Injectable Suspension · 0.5 MG/ML Oral Suspension · 2 MG/ML Oral Suspension · 0.4 MG/ML Oral Solution · 10 MG Oral Tablet · 2 MG Oral Tablet · 5 MG Oral Tablet · 100 MG/ML Nasal Spray · 50 MG/ML Nasal Spray · 75 MG/ML Nasal Spray · 1 MG/ML Oral Solution · 5 MG/ML Oral Solution · 5 MG/ML Injectable Solution

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?