Dapagliflozin And Saxagliptin

What it’s used for

Dapagliflozin and saxagliptin tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Limitations of Use Dapagliflozin and saxagliptin tablets are not recommended for use to improve glycemic control in patients with type 1 diabetes mellitus [ see WARNINGS AND PRECAUTIONS (5.

How to take it

Assess renal function before initiation of therapy and periodically thereafter. ( 2.

Important warnings

Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis : Consider ketone monitoring in patients at risk for ketoacidosis, as indicated. Assess for ketoacidosis regardless of presenting blood glucose levels and discontinue dapagliflozin and saxagliptin if ketoacidosis is suspected.

Common side effects

The following important adverse reactions are described below or elsewhere in the labeling: Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis [see WARNINGS AND PRECAUTIONS (5. 1) ] Pancreatitis [see WARNINGS AND PRECAUTIONS (5.

Interactions

Table 3 : Clinically Relevant Interactions with Dapagliflozin and Saxagliptin Strong Inhibitors of CYP3A4/5 Enzymes Clinical Impact Ketoconazole significantly increased saxagliptin exposure.

If pregnant or breastfeeding

8.

Forms & strengths

10 MG Oral Tablet · 5 MG Oral Tablet · 10 MG / 5 MG Oral Tablet · 5 MG / 5 MG Oral Tablet

Questions to ask your doctor or pharmacist

• Is this the right medicine for my condition, and how long should I take it?
• What side effects should I watch for, and which need urgent attention?
• Does this interact with my other medicines, supplements, or alcohol?
• What should I do if I miss a dose or take too much?