Colchicine

Also sold as colchicine, Colchicine

Medicine summary · from official FDA labels · Oct 19, 2026

1 recall on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Colchicine tablets are an alkaloid indicated for: · Familial Mediterranean fever (FMF) in adults and children 4 years or older ( 1. 2 ).

How to take it

The long-term use of colchicine is established for FMF. The recommended dosage of colchicine tablets depends on the patient’s age, renal function, hepatic function and use of coadministered drugs [see Dosage and Administration ( 2.

Important warnings

5 WARNINGS AND PRECAUTIONS · Fatal overdoses have been reported with colchicine in adults and children. Keep colchicine tablets out of the reach of children ( 5.

Common side effects

Gastrointestinal tract adverse effects are the most frequent side effects in patients initiating colchicine tablets, usually presenting within 24 hours, and occurring in up to 20% of patients given therapeutic doses. Typical symptoms include cramping, nausea, diarrhea, abdominal pain and vomiting.

Interactions

Colchicine is a substrate of the efflux transporter P-glycoprotein (P-gp).

If pregnant or breastfeeding

Forms & strengths

0.6 MG Oral Capsule · 0.5 MG Oral Tablet · 0.6 MG Oral Tablet · 0.5 MG / 500 MG Oral Tablet · 0.12 MG/ML Oral Solution

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?