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Ciprofloxacin Hydrochloride

Also sold as CILOXAN, Ciprofloxacin, Ciprofloxacin Hydrochloride

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: WARNING: SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS Fluoroquinolones, including ciprofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together [see Warnings and Precautions (5. 1) ] including: Tendinitis and tendon rupture [see Warnings and Precautions (5.
8 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Ciprofloxacin tablet is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with the following infections caused by designated, susceptible bacteria and in pediatric patients where indicated: Skin and Skin Structure Infections (1. 1) Bone and Joint Infections (1.

How to take it

Ciprofloxacin tablets should be administered orally as described in the appropriate Dosage Guidelines tables. Adult Dosage Guidelines Infection Dose Frequency Duration Skin and Skin Structure 500 to 750 mg every 12 hours 7 to 14 days Bone and Joint 500 to 750 mg every 12 hours 4 to 8 weeks Complicated Intra- Abdominal 500 mg every 12 hours 7 to 14 days Infectious Diarrhea 500 mg every 12 hours 5 to 7 days Typhoid Fever 500 mg every 12 hours 10 days Uncomplicated Gonorrhea 250 mg single dose single dose Inhalational anthrax (post‑-exposure) 500 mg every 12 hours 60 days Plague 500 to 750 mg every 12 hours 14 days Chronic Bacterial Prostatitis 500 mg every 12 hours 28 days Lower Respiratory Tract 500 to 750 mg every 12 hours 7 to 14 days Urinary Tract 250 to 500 mg every 12 hours 7 to 14 days Acute Uncomplicated Cystitis 250 mg every 12 hours 3 days Acute Sinusitis 500 mg every 12 hours 10 days Adults with creatinine clearance 30 to 50 mL/min 250 to 500 mg q 12 h (2.

Important warnings

Hypersensitivity and other serious reactions: Serious and sometimes fatal reactions (for example, anaphylactic reactions) may occur after the first or subsequent doses of ciprofloxacin. Discontinue ciprofloxacin at the first sign of skin rash, jaundice or any sign of hypersensitivity.

Common side effects

The following serious and otherwise important adverse drug reactions are discussed in greater detail in other sections of labeling: Disabling and Potentially Irreversible Serious Adverse Reactions [see Warnings and Precautions (5. 1) ] Tendinitis and Tendon Rupture [see Warnings and Precautions (5.

Interactions

Ciprofloxacin is an inhibitor of human cytochrome P450 1A2 (CYP1A2) mediated metabolism.

If pregnant or breastfeeding

8.

Forms & strengths

3 MG/ML / 0.25 MG/ML Otic Solution · 250 MG Oral Tablet · 750 MG Oral Tablet · 100 MG Oral Tablet · 3 MG/ML Ophthalmic Solution · 50 MG/ML Oral Suspension · 500 MG Oral Tablet · 100 MG/ML Oral Suspension · 2 MG/ML Otic Solution

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?