Apixaban

Also sold as apixaban, ELIQUIS, Apixaban

Medicine summary · from official FDA labels · Oct 19, 2026

Serious warning: BOXED WARNING WARNING: (A) PREMATURE DISCONTINUATION OF APIXABAN INCREASES THE RISK OF THROMBOTIC EVENTS (B) SPINAL/EPIDURAL HEMATOMA (A) PREMATURE DISCONTINUATION OF APIXABAN INCREASES THE RISK OF THROMBOTIC EVENTS Premature discontinuation of any oral anticoagulant, including apixaban, increases the risk of thrombotic events. If anticoagulation with apixaban is discontinued for a reason other than pathological bleeding or completion of a course of therapy, consider coverage with another anticoagulant [see Dosage and Administration (2.

What it’s used for

Apixaban is a factor Xa inhibitor indicated: to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. ( 1.

How to take it

Reduction of risk of stroke and systemic embolism in nonvalvular atrial fibrillation: The recommended dose is 5 mg orally twice daily. ( 2.

Important warnings

Apixaban can cause serious, potentially fatal, bleeding. Promptly evaluate signs and symptoms of blood loss.

Common side effects

The following clinically significant adverse reactions are discussed in greater detail in other sections of the prescribing information. • Increased risk of thrombotic events after premature discontinuation [see Warnings and Precautions ( 5.

Interactions

Apixaban is a substrate of both CYP3A4 and P-gp.

If pregnant or breastfeeding

Forms & strengths

2.5 MG Oral Tablet · 5 MG Oral Tablet · 0.15 MG Oral Suspension · 0.5 MG Oral Suspension

Questions to ask your doctor or pharmacist

Is this the right medicine for my condition, and how long should I take it?
What side effects should I watch for, and which need urgent attention?
Does this interact with my other medicines, supplements, or alcohol?
What should I do if I miss a dose or take too much?