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Acetaminophen, Diphenhydramine

Also sold as Pain Relief PM

Medicine summary · from official FDA labels · Oct 19, 2026

6 recalls on record — a recall affects specific batches; check with your pharmacist.

What it’s used for

Uses: temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

How to take it

Directions: ■ do not take more than directed (see overdose warning) adults and children 12 years and over ■ take 2 caplets at bedtime ■ do not take more than 2 caplets in 24 hours unless directed by a doctor ■ children under 12 years do not use

Important warnings

Warnings: Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ■ more than 4,000 mg of acetaminophen in 24 hrs ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product.

If pregnant or breastfeeding

If pregnant or breast-feeding ask a health professional before use.

Questions to ask your doctor or pharmacist

  • Is this the right medicine for my condition, and how long should I take it?
  • What side effects should I watch for, and which need urgent attention?
  • Does this interact with my other medicines, supplements, or alcohol?
  • What should I do if I miss a dose or take too much?