A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain:
- Starts between meals or during the night
- Briefly stops if you eat or take antacids
- Lasts for minutes to hours
- Comes and goes for several days or weeks
Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse.
To see if you have an H. pylori infection, your doctor will test your blood, breath, or stool. Your doctor also may look inside your stomach and duodenum by doing an endoscopy or x-ray.
Peptic ulcers will get worse if not treated. Treatment may include medicines to reduce stomach acids or antibiotics to kill H. pylori. Antacids and milk can't heal peptic ulcers. Not smoking and avoiding alcohol can help. You may need surgery if your ulcers don't heal.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
Courtesy of MedlinePlus, from the U.S. National Library of Medicine. Read the full topic on MedlinePlus
Medicines whose label mentions peptic ulcer
These medicines list it among their uses on the official FDA label. This is not a treatment recommendation: only a clinician who knows your history can decide what’s right for you.
When to get urgent help
If symptoms come on suddenly, are severe, or you’re worried, call your local emergency number or go to the nearest emergency department. For anything less urgent, contact your doctor.
Questions to ask your doctor
- What is the likely cause in my case, and what tests might I need?
- What are my treatment options, and what are the trade-offs?
- Which symptoms mean I should seek urgent care?
- What changes to diet, activity or habits would help?